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Gantrisin

Generic name: Sulfisoxazole acetyl

Gantrisin is a children's medication prescribed for the treatment of severe, repeated, or long-lasting urinary tract infections. These include pyelonephritis (bacterial kidney inflammation), pyelitis (inflammation of the part of the kidney that drains urine into the ureter), and cystitis (inflammation of the bladder).

Gantrisin Dosage

• The usual dose for children 2 months of age or older is 150 milligrams per 2.2 pounds of body weight divided into 4 to 6 doses taken over 24 hours.
• The usual starting dose is one-half of the regular dose, or 75 milligrams per 2.2 pounds of body weight divided into 4 to 6 doses taken over 24 hours. Doses should not exceed 6 grams over 24 hours.

Uses of Gantrisin

• This drug is also used to treat bacterial meningitis, and is prescribed as a preventive measure for children who have been exposed to meningitis.
• Gantrisin is also used in the treatment of bacterial infections such as trachoma and inclusion conjunctivitis
• This combination of medication is used to treat infections of the urinary tract (kidney, bladder).

Side Effects of Gantrisin

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for your child to continue taking Gantrisin. Side effects may include:

• Abdominal bleeding
• abdominal pain
• allergic reactions
• anemia and other blood disorders
• angioedema (swelling of face, lips, tongue and throat)
• anxiety
• bluish discoloration of the skin
• chills
• colitis
• convulsions
• cough

Warnings and precautions before taking Gantrisin:

• If your child has impaired kidney or liver function, or severe allergies or bronchial asthma, make sure your doctor knows about it. Caution should be exercised when taking Gantrisin.
• An analysis of urine and kidney function should be performed by your doctor during treatment with Gantrisin, especially if your child has a kidney problem.
• If your child develops a skin rash, stop Gantrisin therapy and call your doctor. Also notify the doctor if your child develops diarrhea.
• This medication may make you more sensitive to the sun. Avoid prolonged sun exposure; use a sunscreen and wear protective clothing when outdoors.
• This medication can affect the results of some diabetic urine testing products (cupric sulfate-type). Consult your doctor or pharmacist for recommendations.

Drug Interaction :- If Gantrisin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Gantrisin with the following:

• Blood-thinning drugs such as Coumadin
  
• Methotrexate, an anticancer drug
  
• Oral diabetes drugs such as Micronase

Overdose

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek emergency medical treatment immediately. Symptoms of an overdose of Gantrisin include:

• Blood or sediment in the urine, blue tinge to the skin, colic, dizziness, drowsiness, fever, headache, lack or loss of appetite, nausea, unconsciousness, vomiting, yellowing of skin and whites of eyes