Generic name: Ursodiol
Actigall (Ursodiol) is an oral gallstone solubilizing agent intended for dissolution of radiolucent gallstones. It also is used to treat primary biliary cirrhosis. This agent is a naturally occurring bile acid, found in small quantities in normal human bile, that suppresses hepatic synthesis, secretion of cholesterol, and the intestinal absorption of cholesterol.
Ursodiol decreases the amount of cholesterol in bile and bile stones by reducing the amount of cholesterol the liver produces. Ursodiol reduces the amount of cholesterol that is absorbed from food and increases the breakdown of cholesterol, especially cholesterol that has formed into stones in the gallbladder. Ursodiol also changes the make-up of the bile acid pool, creating an increase in bile flow in patients with primary biliary cirrhosis.
Uses of Actigall
Side Effects of Actigall
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Actigall. Side effects may include:
Warnings and precautions before taking Actigall:
Drug Interaction :- If Actigall or Urso are taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Actigall or Urso with the following:
Although there have been no reports of overdose with Actigall, the most likely symptom of severe overdose would be diarrhea. Since any medication taken in excess can have serious consequences, you should seek medical attention immediately if you suspect an Actigall overdose.
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