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Kaletra

lopinavir and ritonavir (low PIH na veer and rih TAH na veer)

Kaletra is a combination of two drugs, lopinavir and ritonavir (Norvir), both of which fall into the drug category known as protease inhibitors. When taken along with other HIV drugs, Kaletra lowers the amount of the virus circulating in the bloodstream. However, it does not completely eradicate the virus, and you may continue to develop the rare infections that attack when the immune system weakens. It's also important to remember that Kaletra does not eliminate the danger of transmitting the virus to others.

Kaletra Dosage

• Three capsules twice each day or
• Two tablets twice each day.
• Four capsules twice per day when used with Sustiva or Viramune .
• To improve adherence, Kaletra can be taken as 6 capsules once daily.

It is very important to take this medication on a regular basis as prescribed. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Uses of Kaletra

• This combination product is used, along with other medications, to treat Human Immunodeficiency Virus (HIV) infection. These medications belong to a class of drugs called protease inhibitors that block an enzyme needed for HIV to multiply. Decreasing the amount of HIV in your body helps reduce complications, such as infections (opportunistic types such as pneumocystis pneumonia). This product does not cure HIV.

Side Effects of Kaletra

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Kaletra. Side effects may include:

• Abdominal pain, diarrhea, headache, nausea, rash, vomiting, weakness

Warnings and precautions before taking Kaletra:

• Kaletra has been known to raise blood sugar levels, and can even cause diabetes. If you already have diabetes, be sure to monitor your blood sugar carefully and to notify your doctor if your blood sugar becomes difficult to control.
• Do not take St. John's Wort when taking a Kaletra
• Liver failure, including some fatalities, has been reported among patients on Kaletra. Be sure your doctor knows if you have a history of liver disease, including hepatitis. You will need to be monitored carefully.
• It is not known whether Kaletra passes into breast milk and what effect it may have on a nursing baby. To prevent transmission of the virus to uninfected babies, it is recommended that HIV-positive mothers not breastfeed.

Drug Interaction :- Listed below are some of the other drugs that may interact with Kaletra. However, because interactions are so likely, it's best to check with your doctor before combining Kaletra with any medication, including over-the-counter products and herbal remedies.

• Anticonvulsants such as Dilantin, Phenobarbital, Tegretol
• Antifungals such as Nizoral and Sporanox
• Atovaquone (Mepron)
• Certain cholesterol-lowering agents, including Lipitor, Mevacor, and Zocor
• Certain HIV drugs such as Sustiva, Videx, Viramune
• Clarithromycin (Biaxin)
• methylergonovine

Overdose

Little is known about Kaletra overdose. Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

• Kaletra oral solution contains a high percentage of alcohol, which could be dangerous to a young child. If a child swallows more than the recommended dose, contact your local poison control center immediately.